Download Aquaporins: 190 (Handbook of Experimental Pharmacology) by Eric Beitz PDF

By Eric Beitz

The aquaporin box has matured at a very quick velocity and we're on the verge to improve severe recommendations to therapeutically modulate aquaporin functionality without delay or through regulatory networks. Key necessities can be found this present day: i. a substantial (and becoming) variety of aquaporin crystal constructions for the rational layout of inhibitory molecules, ii. tricky molecular dynamics simulation options for theoretical analyses of selectivity mechanisms and docking experiments, iii. finished info on aquaporin immunohistochemistry, iv. aquaporin knockout animals for physiological reports, and v. assay structures for compound library screenings. The constitution of this quantity on aquaporins follows the issues laid out above and hence covers the advancements from uncomplicated examine to strength pharmacological use. located among pharmacology textbooks and up to date clinical papers this e-book offers a well timed assessment for readers from the elemental in addition to the utilized disciplines.

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